Studies and research

Patients followed at the Epatocentro Ticino, the main partner of the Foundation, have access to state-of-the-art diagnostic methods and therapeutic options and, participating in clinical trials, to innovative treatments often years before they enter the market.


PATHOLOGY
STUDY TYPE
STATUS
RECRUITMENT
A Study to Evaluate the Safety and Effect of the Experimental Drugs ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Subjects With Chronic Hepatitis C (PEARL-II)
PATHOLOGY: Hepatitis C Virus HCV
A Study to Evaluate Chronic Hepatitis C Infection
PATHOLOGY: Hepatitis C Virus HCV

Named Patient/Compassionate Use Program of Simeprevir in patients with chronic genotype 1 or 4 HCV infection who are clinically compensated (Child Pugh A or B), ineligible to receive IFN and have not undergone liver transplantation

PATHOLOGY: Hepatitis C Virus HCV
A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Subjects With Genotype 1 Infection
PATHOLOGY: Hepatitis C Virus HCV
A Study Comparing Efficacy and Safety of ABT-493/ABT-530 to Sofosbuvir Dosed With Daclatasvir in Adults With HCV Genotype 3 Infection (ENDURANCE-3)
PATHOLOGY: Hepatitis C Virus HCV
Assessment of liver stiffness in HCV infected patients undergoing antiviral treatment with new DAA
PATHOLOGY: Hepatitis C Virus HCV
The Health Burden of Primary Biliary Cirrhosis in Switzerland
PATHOLOGY: Primary Biliary Cholangitis
Seroprevalence of liver autoantibodies in patients with acute hepatitis E infection
PATHOLOGY: Hepatitis E Virus HEV
A Phase IV Trial of Paritaprevir/Ritonavir, Ombitasvir, Dasabuvir for Chronic Hepatitis C Genotype 1 Virus Infection (D3FEAT)
PATHOLOGY: Hepatitis C Virus HCV
Retrospective analysis of the outcomes of HCV infected individuals in the hospital setting in Switzerland
PATHOLOGY: Hepatitis C Virus HCV

Liver autoantibodies in patients with chronic hepatitis C infection treated by direct acting antiviral agents

PATHOLOGY: Hepatitis C Virus HCV

Quality of Life Measurement in Treatment Naïve Patients With HCV Genotype 1 Suffering From Fatigue and Receiving Ombitasvir, Paritaprevir, and Ritonavir and Dasabuvir (Viekirax®/Exviera®) (HEMATITE)

PATHOLOGY: Hepatitis C Virus HCV
Study of the Effectiveness and Clinical Practice Use of Glecaprevir Plus Pibrentasvir in Patients With Chronic Hepatitis C Genotypes 1 to 6
PATHOLOGY: Hepatitis C Virus HCV
Phase 2b Study in NASH to Assess IVA337 (NATIVE)
PATHOLOGY: Non-alcoholic Statohepatitis NASH
A Two-year Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis
PATHOLOGY: Hereditary Hemochromatosis
Safety, Tolerability, and Efficacy of a Combination Treatment of Tropifexor (LJN452) and Cenicriviroc (CVC) in Adult Patients With Nonalcoholic Steatohepatitis (NASH) and Liver Fibrosis (TANDEM)
PATHOLOGY: Non-alcoholic Statohepatitis NASH
Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH
PATHOLOGY: Non-alcoholic Statohepatitis NASH
ADCC Mediated B-Cell dEpletion and BAFF-R Blockade (AMBER)
PATHOLOGY: Autoimmune Hepatitis
Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in PWID and People With HIV Coinfection (REACT)
PATHOLOGY: Hepatitis C Virus HCV
Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment (REGENERATE)
PATHOLOGY: Non-alcoholic Statohepatitis NASH
Autoimmune Idiopathic Disorders in HCV patients: Effect of direct Antiviral Agents (DAA)
PATHOLOGY: Hepatitis C Virus HCV
Swiss Liver Venous Thrombosis Study
PATHOLOGY: Portal Vein Thrombosis
Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis (STELLAR 3)
PATHOLOGY: Non-alcoholic Statohepatitis NASH
Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (STELLAR 4)
PATHOLOGY: Non-alcoholic Statohepatitis NASH
Reducing the Burden of Influenza after Solid-Organ Transplantation: the STOP-FLU trial [Swiss Trial in solid Organ transplantation on Prevention of inFLUenza]
PATHOLOGY: Transplant
Swiss Hepatitis B Cohort Study
PATHOLOGY: Hepatitis B Virus HBV
Swiss Hepatitis C Cohort Study (SCCS)
PATHOLOGY: Hepatitis C Virus HCV
Swiss HIV Cohort Study (SHCS)
PATHOLOGY: Human Immunodeficiency Virus HIV
The Swiss Transplant Cohort Study (STCS)
PATHOLOGY: Transplant
The Swiss Association for the Medical Management in Substance Users (SAMMSU)
PATHOLOGY: Autoimmune Hepatitis
Swiss Autoimmune Hepatitis Cohort Study SASL3
PATHOLOGY: Autoimmune Hepatitis
Swiss Primary Biliary Cholangitis Cohort Study SASL39
PATHOLOGY: Primary Biliary Cholangitis
Swiss Primary Sclerosing Cholangitis Cohort Study SASL40
PATHOLOGY: Primary Sclerosing Cholangitis