Studies and research

Through the Foundation research is turned into reality enabling patients in the Epatocentro to access cutting edge therapeutic opportunities and, in the context of a clinical study, innovative treatments 1 - 2 years before they are released onto the market.

 

Clinical studies and research

The Foundation actively participates in clinical research protocols especially in the field of new drugs for the treatment of chronic hepatitis C, hepatitis B and other hepatic diseases;

The contribution made by the centre in this field is evidenced by the results achieved including:

  • Development of Entecavir, effective drug for the treatment of chronic hepatitis B;
  • Drawing up and implementing a programme for the prevention and screening of viral hepatitis (B and C) and chronic alcoholism in a high risk population in Italian Switzerland; it is a pilot project at national level.

Epidemiological research

The centre participates in projects supported by national bodies and research laboratories such as:

Swiss Cohort Study for Hepatitis C

  • 4,000 patients with hepatitis C involved throughout Switzerland;
  • Initiated by Swiss Experts in Viral Hepatitis (SEVHep), has seen in Lugano one of the founding centres and a partner active in research projects carried out with the Cantonal Microbiology Institute (ICM);
  • Various research studies carried out with the data collected have, inter alia, made it possible to discover genetic factors in persons affected by hepatitis C which determine the progress and response to anti-viral treatment.
  • More information on the study

Swiss Cohort Study of transplant patients

  • The study aims to monitor the state of health of transplant patients, identify problems and propose solutions;
  • The centre actively participates in this national project and supplies data regarding liver transplant patients in treatment;
  • Collaboration with the liver transplant centres of Berne and Geneva enhances the quality of care and network research projects.
  • More information on the study

Swiss HIV Cohort Study (SHCS)

  • Set up in 1988, it has enrolled 18,416 patients with HIV infection throughout Switzerland. It has always made an active contribution to clinical research on HIV infection and antiretroviral therapy (40 high level international publications in 2013 alone);
  • It has always made an active contribution to clinical research on HIV infection and antiretroviral therapy (40 high level international publications in 2013 alone);
  • Important collaboration with other major international studies (e.g. DAD study) and numerous sub-studies (e.g. Mother and Child which involves HIV positive pregnant women and their children).
  • More information on the study

Clinical pharmacology

  • The centre also devotes attention to clinical pharmacology aimed at improving the correct use of drugs.